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研究論文及專書目錄:

A. 期刊論文 (Peer review papers)

1. Chao, C.C.-K. and Rosenstein, B.S. Inhibition of the UV induction of sister-chromatid exchanges in ICR 2A frog cells by pretreatment with gamma-rays. Mutat. Res. 139: 35-39, 1984.

 

2. Chao, C.C.-K. and Rosenstein, B.S. Induction of sister-chromatid exchanges in ICR 2A frog cells exposed to 254 nm and solar wavelengths. Photochem. Photobiol. 41: 625-627, 1985.

 

3. Chao, C.C.-K., Rosenstein, R.B. and Rosenstein, B.S. Induction of sister-chromatid exchanges in ICR 2A frog cells exposed to 265-313 nm monochromatic ultraviolet wavelengths and photoreactivating light. Mutat. Res. 149: 443-450, 1985.

 

4. Rosenstein, B.S. and Chao, C.C.-K. Isolation of a mutant cell line derived from ICR 2A frog cells hypersensitive to the induction of nondimer DNA damage by solar ultraviolet radiation. Somatic Cell Mol. Genet. 11: 339-344, 1985.

 

5. Rosenstein, B.S., Chao, C.C.-K. and Ducore, J.M. Analysis of the excision repair of nondimer DNA damage induced by solar ultraviolet radiation in ICR 2A frog cells. Radiat. Res. 103: 286-292, 1985.

 

6. Rosenstein, B.S. and Chao, C.C.-K. Characterization of DNA repair in a mutant cell line derived from ICR 2A frog cells that is hypersensitive to non-dimer DNA damages induced by solar ultraviolet radiation. Mutat. Res. 146: 191-196, 1985.

 

7. Chao, C.C.-K. and Rosenstein, B.S. Use of metabolic inhibitors to investigate the excision repair of pyrimidine dimers and non-dimer DNA damages induced in human and ICR 2A frog cells by solar ultraviolet radiation. Photochem. Photobiol. 43: 165-170, 1986.

 

8. Rosenstein, B.S., Chao, C.C.-K. and Ducore, J.M. The use of metabolic inhibitors to compare the excision repair of pyrimidine dimers and nondimer DNA damages in human skin fibroblasts exposed to 254-nm and sunlamp-produced 310-nm ultraviolet radiation. Environ. Mol. Mutagen. 8: 335-343, 1986.

 

9. Mitchell, D.L., Clarkson, J.M., Chao, C.C.-K. and Rosenstein, B.S. Repair of cyclobutane dimers and (6-4) photoproducts in ICR 2A frog cells. Photochem. Photobiol. 43: 595-597, 1986.

 

10. Chao, C.C.-K. and Lin-Chao, S. Transient induction of photolyase activity in arrested frog cells in response to a short-wave ultraviolet segment of simulated "sunlight". Biochem. Biophys. Res. Comm. 145: 604-611, 1987.

 

11. Chao, C.C.-K. and Lin-Chao, S. Regulation of photorepair in growing and arrested frog cells in response to ultraviolet light. Mutat. Res. 192: 211-216, 1987.

 

12. Chao, C.C.-K. and Lin-Chao, S. Loss of inducible photorepair in a frog cell mutant hypersensitive to solar UV. FEBS Lett. 225: 133-138, 1987.

 

13. Chao, C.C.-K., Bird, P., Gething, M.-J. and Sambrook, J. Post-translational translocation of influenza virus hemagglutinin across microsomal membranes. Mol. Cell. Biol. 7: 3842-3845, 1987.

 

14. Chao, C.C.-K., Bird, P., Gething, M.-J. and Sambrook, J. Uncoupling of translocation across microsomal membranes from biosynthesis of influenza virus hemagglutinin. In: Molecular Biology of Intracellular Protein Sorting and Organelle Assembly, (UCLA Symp. Molec. Cell. Biol.) pp. 85-91, New York: Alan R. Liss, Inc., 1988.

 

15. Gething, M.-J., McCammon, K., Normington, K., Chao, C.C.-K. and Sambrook, J. Protein folding and intracellular transport. In: Molecular Biology of Intracellular Protein Sorting and Organelle Assembly, (UCLA Symp. Molec. Cell. Biol.), New York: Alan R. Liss, Inc., 1988.

 

16. Chao, C.C.-K. and Bird, P. Uncoupling of translocation across microsomal membranes from biosynthesis of influenza virus hemagglutinin. J. Cell. Biochem. 36: 289-295, 1988.

 

17. Chao, C.C.-K., Lee, Y.-L. and Lin-Chao, S. Phenotypic reversion of cisplatin resistance accompanies reduced host cell reactivation of damaged plasmid. Biochem. Biophys. Res. Comm. 170: 851-859, 1990.

 

18. Chao, C.C.-K., Yam, W.-C. and Lin-Chao, S. Coordinated induction of two unrelated glucose-regulated protein genes by a calcium ionophore: human BiP/GRP78 and GAPDH. Biochem. Biophys. Res. Comm. 171: 431-438, 1990.

 

19. Chao, C.C.-K., Ma, C.M., Cheng, P.-W. and Lin-Chao, S. Increased mdr gene expression and decreased drug accumulation in a human colonic cancer cell line resistant to hydrophobic drugs. Biochem. Biophys. Res. Comm. 172: 842-849, 1990.

 

20. Chao, C.C.-K., Lee, Y.-L., Cheng, P.-W. and Lin-Chao, S. Enhanced host cell reactivation of damaged plasmid DNA in HeLa cells resistant to cis-diamminedichloroplatinum(II). Cancer Res. 51: 601-605, 1991.

 

21. Chao, C.C.-K. Increase in damaged-DNA binding and repair in human UV resistance. In: Trends in Photochemistry and Photobiology 1: 341-351, ed. Council of Scientific Research Integration, India, India: Research Trends, 1991.

 

22. Chao, C.C.-K., Huang, S.-L., Huang, H. and Lin-Chao, S. Cross resistance to UV radiation of a cisplatin-resistant human cell line: Overexpression of cellular factors that recognize UV-modified DNA. Mol. Cell. Biol. 11: 2075-2080, 1991.

 

23. Chao, C.C.-K., Huang, S.-L., Lee, L.-Y. and Lin-Chao, S. Identification of inducible damage-recognition proteins that are overexpressed in HeLa cells resistant to cis-diamminedichloroplatinum(II). Biochem. J. 277: 875-878, 1991.

 

24. Chao, C.C.-K. Potential negative regulation of damage-recognition proteins in cisplatin resistant HeLa cells in response to DNA damage. Mutat. Res. 264: 59-66, 1991.

 

25. Chao, C.C.-K., Ma, C.M. and Lin-Chao, S. Co-amplification and over-expression of two mdr genes in a multidrug-resistant human colon carcinoma cell line. FEBS Lett. 291: 214-218, 1991.

 

26. Chao, C.C.-K., Huang, S.-L. and Lin-Chao, S. Ca2+-mediated inhibition of a nuclear protein that recognizes UV-damaged DNA and is constitutively overexpressed in resistant human cells: DNA-binding assay. Nucleic Acids Res. 19: 6413-6418, 1991

 

27. Chao, C.C.-K. Damage-recognition proteins as a potential indicator of DNA damage-mediated sensitivity or resistance of human cells to ultraviolet radiation. Biochem. J. 282: 203-207, 1992.

 

28. Chao, C.C.-K. A single amino acid deletion at the N-terminus of influenza virus hemagglutinin causes malfolding and prevents transport of the molecule from endoplasmic reticulum in mammalian cells. J. Biol. Chem. 267: 2142-2148, 1992.

 

29. Chao, C.C.-K., Huang, Y.-T., Ma, C.M., Chou, W.-Y. and Lin-Chao, S. Overexpression of glutathione S-transferase and elevated thiol pools in a multidrug-resistant human colon cancer cell line. Mol. Pharmacol. 41: 69-75, 1992.

 

30. Chao, C.C.-K. Characterization of a UV-damage recognition factor in vitro that is associated with UV resistance in HeLa cells. Mutat. Res. 281: 105-113, 1992

 

31. Chao, C.C.-K., Yam, W.-C., Chen, L.-K. and Lin-Chao, S. Cloning of a functional Burkitt's lymphoma polypeptide-binding protein/78 kDa glucose-regulated protein (BiP/GRP78) gene promoter by the polymerase chain reaction, and its interaction with inducible cellular factors. Biochem. J. 286: 555-559, 1992

 

32. Chao, C.C.-K. and Lin-Chao, S. A direct-repeat sequence of the human BiP gene is required for A23187-mediated inducibility and an inducible factor binding. Nucleic Acids Res. 20: 6481-6485, 1992

 

33. Chao, C.C.-K. Overproduction of damage recognition proteins in human cells resistant to cisplatin and ultraviolet radiation. In: Gene Amplification in Mammalian Cells: A comprehensive guide, pp. 131-139, ed. R.E. Kellems, USA: Marcel Dekker, Inc., 1993.

 

34. Chao, C.C.-K., Sun, N.-K. and Lin-Chao, S. Characterization of a DNA damage recognition protein from F9 teratocarcinoma cells, which is inducible by retinoic acid and cAMP. Biochem. J. 290: 129-134, 1993 .

 

35. Song, E.-J., Chiang, C.-D., Chao, C.C.-K. and Cheng, V. The efflux of intracellular vincristine in drug-resistant human lung cancer cells is not mediated by P-glycoprotein. J. Formosan Med. Assoc. 92: S69-75, 1993

 

36. Chao, C.C.-K. and Sun, N.-K. Overproduction of a UV-modified DNA recognition protein in a UV-sensitive human colon cancer cell line that features MDR phenotype. Biochem. Biophy. Res. Comm. 191: 1252-1260, 1993

 

37. Chao, C.C.-K. and Huang, S.-L. Inhibition of UV-damaged DNA recognition activity in HeLa cells by calcium ionophore A23187: Potential involvement of cytosolic proteins. Biochem. Biophys. Res. Comm. 193: 764-770, 1993

 

38. Chao, C.C.-K. Constitutive over-production of DNA-damage recognition proteins and acquired UV resistance in prolonged culture of F9 teratocarcinoma stem cells. FEBS Lett. 329: 253-258, 1993

 

39. Chao, C.C.-K. and Huang, S.-L. Apparent alterations in the early stage of excision repair of UV-induced DNA damages in a HeLa mutant cell line that is resistant to genotoxic stresses. Mutat. Res. 303: 19-27, 1993

 

40. Chao, C.C.-K. Lack of DNA enzymatic photoreactivation in HeLa cell-free extracts. FEBS Lett. 336: 411-416, 1993

 

41. Lin-Chao, S. and Chao, C.C.-K. Reduced inhibition of DNA synthesis and G2 arrest in the cell cycle progression of resistant HeLa cells in response to cis-diamminedichloroplatinum(II). J. Biomed. Sci. 1: 131-138, 1994

 

42. Chiang, C.-D., Song, E.-J., Yang, V.C. and Chao, C.C.-K. Ascorbic acid increases drug accumulation and reverses vincristine resistance of human non-small cell lung cancer cells. Biochem. J. 301: 759-764, 1994

 

43. Chao, C.C.-K. Decreased accumulation as a mechanism of resistance to cis-diamminedichloroplatinum(II) in cervix carcinoma HeLa cells: Relation to DNA repair. Mol. Pharmacol. 45: 1137-1144, 1994

 

44. Chao, C.C.-K. Enhanced excision repair of DNA damage due to cis-diamminedichloroplatinum(II) in resistant cervix carcinoma HeLa cells. Eur. J. Pharmacol. 268: 347-355, 1994

 

45. Chao, C.C.-K., Shieh, T.-C. and Huang, H. Use of a monoclonal antibody to detect DNA damage caused by anticancer drug cis-diamminedichloroplatinum(II) in vivo and in vitro. FEBS Lett. 354: 103-109, 1994

 

46. Song, E.-J., Yang, V.C., Chiang, C.D. and Chao, C.C.-K. Potentiation of growth inhibition due to vincristine by ascorbic acid in a resistant human non-small cell lung cancer cell line. Eur. J. Pharmacol. 292: 119-125, 1995

 

47. Chao, C.C.-K., Yam, W.-C., Chung, K.-C. and Ho, Y.-S. Adriamycin-inducible proteins associated with drug sensitivity in resistant immunoblastic B lymphoma cells. Mutat. Res. 346: 33-41, 1995

 

48. Chao, C.C.-K. Lack of elevated drug efflux in adriamycin-resistant immunoblastic B lymphoma cells with MDR1 gene overexpression. FEBS Lett. 373: 285-290, 1995

 

49. Huang, H.S., Peng, J.T., She, J.Y., Zhang, L.P., Chao, C.C.-K., Liu, K.H., She, J.X. HLA-encoded susceptibility to insulin-dependent diabetes mellitus is determined by DR and DQ genes as well as their linkage disequilibria in a Chinese population. Human Immunol. 44: 210-219, 1995

 

50. Sun, N.-K., Huang, S.-L., Lin-Chao, S. and Chao, C.C.-K. Induction, not associated with host cell reactivation of damaged plasmid DNA, of DNA-damage recognition proteins by retinoic acid and cAMP in mammalian cells. Biochem. J. 313: 441-445, 1996

 

51. Chao, C.C.-K. Selective drug efflux in multidrug-resistant immunoblastic B lymphoma cells with overexpressed P-glycoprotein. Eur. J. Pharmacol.- Environ. Toxicol. Pharmacol. 1: 63-72, 1996

 

52. Chao, C.C.-K. Inhibition by arsenite of anticancer drug cis-diamminedichloroplatinum(II) induced DNA repair and drug resistance in HeLa cells. Eur. J. Pharmacol. - Envron. Toxicol. Pharmacol. 1: 199-205, 1996

 

53. Chao, C.C.-K. Cross-resistance to cis-diamminedichloroplatinum(II) of an MDR lymphoma cell line associated with decreased drug accumulation and enhanced DNA repair. Eur. J. Pharmacol. - Mol. Pharmacol. 305: 213-222, 1996

 

54. Chao, C.C.-K. Molecular basis of cis-diamminedichloroplatinum(II) resistance: a review. J. Formosan Med. Assoc. 95: 893-900, 1996

 

55. Ju, Y.T., Chang, A.C.Y., She, B.-R., Tsau, M.-L., Chao, C.C.-K., Hwang, H.-M., Cohen, S.N. and Lin-Chao, S. Gas7, a mouse novel gene expressed preferentially during growth arrest of fibroblasts and in terminally differentiated Purkinje neurons is required for neurite formation. Proc. Natl. Acad. Sci. USA 95: 11423-11428, 1998

 

56. Lo, Y.-F., Chen, T.-C., Chen, S.-C. and Chao, C.C.-K. Aberrant expression of TSG101 in Taiwan Chinese breast cancer. Breast Cancer Res. Treat. 60: 259-266, 2000 [IF: 4.67]

 

57. Kamarajan, P. and Chao, C.C.-K. UV-induced apoptosis in resistant HeLa cells. Bioscience Rep. 20: 99-108, 2000

 

58. Lee, M.-S., Ueng, S.W.-N., Shih, C.-H. and Chao, C.C.-K. Primary cultures of human chondrocytes are susceptible to low inocula of Staphylococcus aureus infection and undergo apoptosis. Scand. J. Infect. Dis. 33: 47-50, 2001

 

59. Lee, M.-S., Yen, C.-Y., Ueng, S.W.-N., Shih, C.-H. and Chao, C.C.-K. Signal transduction pathways and apotosis in bacteria-infected chondrocytes. J. Orthop. Res. 19: 696-702, 2001

 

60. Lee, M.S., Chao, E.K., Ueng, S.W.N., Chen, C.Y., Shih, C.H., and Chao, C.C.-K.. Effects of different mechanical stresses on nitric oxide release influence cartilage macromolecular genes expression in human osteoarthritic chondrocytes in vitro. J Orthop Surg, R.O.C. 18: 1-6, 2001

 

61. Kamarajan, P., Sun, N.-K., Sun, C.-L. and Chao, C.C.-K. Apaf1 overexpression partially overcomes acquired cisplatin resistance in a cisplatin-selected HeLa cell line. FEBS Lett. 505: 206-212, 2001

 

62. Sun, N.-K., Kamarajan, P., Huang, H. and Chao, C.C.-K. Restoration of UV sensitivity in UV-resistant HeLa cells by antisense-mediated depletion of damaged DNA-binding protein 2 (DDB2). FEBS Lett. 512: 168-172, 2002

 

63. Sun, N.-K., Lu, H.-P. and Chao, C.C.-K. Identification of rat DDB1, a putative DNA repair protein, and functional correlation with UV damaged-DNA recognition activity. J. Biomed. Sci. 9: 371-380, 2002

 

64. Sun, N.-K., Lu, H.-P. and Chao, C.C.-K. Overexpression of damaged DNA-binding protein 2 (DDB2) potentiates UV resistance in hamster V79 cells. Chang Gung Med. J. 25: 686-695, 2002

 

65. Chao, C.C.-K., Su, L.-J., Sun, N.-K., Ju, Y.-T., Lih, J.C.-J. and Lin-Chao, S. Involvement of Gas7 in NGF-independent and dependent cell processes in PC12 cell. J. Neurosci. Res. 74: 246-254, 2003

 

66. Kamarajan, P., Sun, N.-K. and Chao, C.C.-K. Upregulation of FLIP in cisplatin-selected HeLa cells causes cross-resistance to Fas death signaling. Biochem J. 376: 253-260, 2003

 

67. Fan, C.W., Chan, C.C., Chao, C.C.-K., Fan, H.A., Sheu, D.L. and Chan, E.-C. Expression patterns of cell cycle and apoptosis-related genes in a multidrug-resistant human colon carcinoma cell line. Scand J Gastroenterol. 39: 464-469, 2004

 

68. Lee, M.S., Tu, Y.K., Chao, C.C.-K., Chen, S.C., Chen, C.Y., Chan, Y.S., Yeh, W.L., Ueng, S.W.N. Inhibition of nitric oxide can ameliorate apoptosis and modulate matrix protein gene expression in bacteria infected chondrocyte in vitro. J. Orthop. Res. 23: 440-445, 2005

 

69. Sun, C.-L. and Chao, C.C.-K. Potential attenuation of p38 signaling by DDB2 as a factor in acquired TNF resistance. Int. J. Cancer 115: 383-389, 2005

 

70. Chang, P.-Y., Kuo, J.-T., Lin-Chao, S. and Chao, C.C.-K. Identification of rat Gas7 isoforms differentially expressed in brain and regulated after kainate-induced neuronal injury. J. Neurosci. Res. 79: 788-797, 2005

 

71. Sun, C.-L. and Chao, C.C.-K. Cross-resistance to death ligand-induced apoptosis, in cisplatin-selected HeLa cells, associated with overexpression of DDB2 and subsequent induction of cFLIP. Mol. Pharmacol. 67: 1307-1314, 2005

 

72. Chao, C.C.-K., Chang, P.-Y. and Lu, H.-P. Human Gas7 isoforms homologous to mouse transcripts differentially induce neurite outgrowth. J. Neurosci. Res. 81: 153-162, 2005

 

73. Sun, N.-K. and Chao, C.C.-K. The cytokine activity of HMGB1, extracellular escape of the nuclear protein (a review). Chang Gung Med. J. 28: 673-682, 2005

 

74. Chao, C.C.-K. Gas7. AfCS-Nature Molecular Page, 2006 (A000068, doi:00.0000/ mp.g000000.00)

 

75. Chao, C.C.-K. Hmg1. AfCS-Nature Molecular Page, 2006 (A001133, doi:00.0000/mp.h000000.00)

 

76. Tsai, S.-Y.*, Sun, N.-K.*, Lu, H.-P., Cheng, M.-L. and Chao, C.C.-K. Involvement of reactive oxygen species in multidrug resistance of a vincristine-selected lymphoblastoma. Cancer Sci. 98: 1206-1214, 2007 (*equal contribution)

 

77. Chang, E.Y.H., Ueng, S.W.N., Lin-Chao, S. and Chao, C.C.-K. Involvement of Gas7 along the ERK 1/2 MAP kinase pathway in chondrogenesis of human marrow derived mesenchymal stem cells. Osteoarthritis Cartilage, 16: 1403-1412, 2008

 

78. Chang, E.Y.H., Hsieh, P.-H. and Chao, C.C.-K. The efficiency of using density gradient medium to isolate human bone marrow stromal cells with multipotential differentiation. Chang Gung Med. J. 32: 264-275, 2009 [長庚醫誌優秀論文獎; 獎金NTD30,000]

 

79. Wu, Z.-Z., Lu, H.-P. and Chao, C.C.-K. Identification and functional analysis of genes which potentially confer resistance to cisplatin in tumor cells. Biochem. Pharmacol. 80: 262-276, 2010

 

80. Sun, N.-K.*, Sun, C.-L.*, Lin, C.-H., Pai, L.-M. and Chao, C.C.-K. Damaged DNA-binding protein 2 (DDB2) protects against UV irradiation in human cells and Drosophila. J. Biomed. Sci., 2010 (*equal contribution)

 

81. Wu, Z.-Z. and Chao, C.C.-K. Knockdown of NAPA using short-hairpin RNA sensitizes cancer cells to cisplatin: implications to overcome chemoresistance. Biochem. Pharmacol. 80: 827-837, 2010

 

82. Kuo, T.-C. and Chao, C.C.-K. Hepatitis B virus X protein prevents apoptosis of hepatocellular carcinoma cells by upregulating SATB1 and HURP expression. Biochem. Pharmacol. 80: 1093-1102, 2010

 

83. Hung, F.-C. and Chao, C.C.-K. Knockdown of growth-arrest-specific 7b gene (gas7b) using short-hairpin RNA desensitizes neuroblastoma cells to cisplatin: implications to prevent apoptosis of neurons. J. Neurosci. Res. 88: 3578-3587, 2010

 

84. Wu, Z.-Z., Sun, N.-K. and Chao, C.C.-K. Knockdown of CITED2 using short-hairpin RNA sensitizes cancer cells to cisplatin through stabilization of p53 and enhancement of p53-dependent apoptosis. J. Cell. Physiol. 226: 2415-2428, 2011

 

85. Chao, C.C.-K. A Search for the genes involved in resistance to cisplatin chemotherapy: Review of the experimental evidence. Curr. Top. Pharmacol. 14: 47-54, 2011 January [invited review article]

 

86. Chao, C.C.-K. The role of DDB2 in regulating cell survival and apoptosis following DNA damage - a mini-review. In DNA Repair (ed., Kruman, I.), InTech: 2011 July (ISBN 978-953-307-697-3) [invited review book chapter]

 

87. Hung, F.-C., Chang, Y.-H., Lin-Chao, S. and Chao, C.C.-K. Gas7 mediates the differentiation of human bone marrow-derived mesenchymal stem cells into functional osteoblasts by enhancing Runx2-dependent gene expression. J. Orthop. Res. 29: 1528-1535, 2011

 

88. Chao, C.C.-K. Chondrogenic differentiation of human mesenchymal stem cells: Role of human growth-arrest-specific protein, SOX9, and extracellular signal-regulated kinase. In Stem Cells and Cancer Stem Cells: Therapeutic Applications in Disease and Injury (ed., Hayat, E.), Springer: 2011 [invited book chapter] dis-connected??

 

89. Kuo, T.-C.*, Lu, H.-P.* and Chao, C.C.-K. The tyrosine kinase inhibitor sorafenib sensitizes hepatocellular carcinoma cells to taxol by suppressing the HURP protein. Biochem. Pharmacol. 82: 184-194, 2011 (*equal contribution)

 

90. Wu, Z.-Z., Sun, N.-K., Chien, K.-Y. and Chao, C.C.-K. Silencing of the SNARE protein NAPA sensitizes cancer cells to cisplatin by inducing ERK1/2 signaling, synoviolin ubiquitination and p53 accumulation. Biochem Pharmacol. 82: 1630-1640, 2011

 

91. Wu, Z.-Z.*, Chow, K.-P.N.*, Kuo, T.-C., Chang, Y.-S., Chao, C.C.-K. Latent membrane protein 1 of Epstein–Barr virus sensitizes cancer cells to cisplatin by enhancing NF-kB p50 homodimer formation and downregulating NAPA expression. Biochem. Pharmacol. 82: 1860-1872, 2011 (*equal contribution)

 

92. Kuo, T.-C., Chang, P.-Y., Huang, S.-F., Chou, C.-K. and Chao, C.C.-K. Knockdown of HURP inhibits the proliferation of hepatocellular carcinoma cells via downregulation of gankyrin and accumulation of p53. Biochem Pharmacol. 83: 758- 768, 2012

 

93. Chao, C.C.-K. Adapting new ways to escape attacks by anti-cancer drugs: Epigenetic changes and alternative splicing. Adaptive Medicine 4: 64-68, 2012 [invited review]

 

94. Sun, N.-K., Huang, S.-L., Chien, K.-Y. and Chao, C.C.-K. Golgi-SNARE GS28 potentiates cisplatin-induced apoptosis by forming GS28/MDM2/p53 complexes and by preventing the ubiquitination and degradation of p53. Biochem. J. 444: 303-314, 2012

 

95. Huang, B.-T., Chang, P.-Y., Su, C.-H., Chao, C.C.-K. and Lin-Chao, S. Deficiency of Gas7 in mice reveals motor coordination defects due to abnormal motor neuron function and muscle fiber composition during aging. PLoS ONE 7(5): e37702, 2012 [doi:10.1371/journal.pone.0037702]

 

96. Lu, H.-P. and Chao, C.C.-K. Cancer cells acquire resistance to anticancer drugs: An update. Biomed. J. 35: 479-491, 2012 [invited review]

 

97. Hung, F.-C., Cheng, Y.-C., Sun, N.-K. and Chao, C.C.-K. Identification and characterization of zebrafish gas7 gene in early development. J, Neurosci. Res. 91:51-61, 2013 [doi: 10.1002/jnr.23145. Epub 2012 Oct 22]

 

98. Chao, C.C.-K, Hung, F.C. and Chao, J.J. Gas7 is required for mesenchymal stem cell-derived bone development. Stem Cells Int. 2013, Article ID 137010. doi:10.1155/2013/137010 [invited review] [originally for cancelled special issue: “New insights into bone development and repair and mesenchymal stem cell differentiation” (eds., Gaël Y. Rochefort, Laoise Mcnamara, Bruno Péault)]

 

99. Sun, N.-K., Huang, S.-L., Chang, T.-C. and Chao, C.C.-K. Sorafenib induces apoptosis in endometrial carcinoma cells by inhibiting Elk-1-dependent Mcl-1 gene expression and by inducing Akt/GSK3β-dependent Mcl-1 protein degradation. J. Cell. Biochem. 114: 1819-1831, 2013

 

100. Chang, P.-Y.*, Wu, Z.-Z.*, Sun, N.-K. and Chao, C.C.-K. EBV-encoded LMP-1 sensitizes nasopharyngeal carcinoma cells to genotoxic drugs by down-regulating Cabin1 expression. J. Cell. Physiol. 229: 309-322, 2014 (first online: 22 Nov. 2013, DOI: 10.1002/jcp.24448) (*equal contribution)

 

101. Sun, N.-K.*, Huang, S.-L.*, Chang, P.-Y., Lu, H.-P. and Chao, C.C.-K. Transcriptomic profiling of taxol-resistant ovarian cancer cells identifies FKBP5 and the androgen receptor as critical markers of chemotherapeutic response. Oncotarget 5: 11939-11956, 2014 (*equal contribution)

 

102. Huang, S.-L. and Chao, C.C.-K. Linking immunophilin FKBP5 to taxol resistance in ovarian cancer. Cancer Cell & Microenviron. 2015; 2: e692. doi: 10.14800/ccm.692 [invited research highlight]

 

103. Chao, C.C.-K. Mechanisms of p53 degradation. Clinica Chimica Acta 438: 139-147, 2015 (first online: 13 Aug. 2014, doi: 10.1016/j.cca.2014.08.015) [invited review]

 

104. Lin, Y.-T., Lu, H.-P. and Chao, C.C.-K. Oncogenic c-Myc and prothymosin-alpha protect hepatocellular carcinoma cells against sorafenib-induced apoptosis. Biochem. Pharmacol. 93: 110-124,

2015 (first online: 3 Nov. 2014, DOI:10.1016/j.bcp.2014.10.012)

 

105. Lin, Y.-T. and Chao, C.C.-K. Sorafenib induces apoptosis in hepatocellular carcinoma Cells by inhibiting c-Myc and prothymosin-alpha. Cancer Cell & Microenviron. 2015; 2: e788. doi: 10.14800/ccm.788 [invited research highlight]

 

106. Huang, S.-L. and Chao, C.C.-K. Silencing of taxol-sensitizer genes in cancer cells: Lack of sensitization effects. Cancers 7: 1052-1071, 2015; doi:10.3390/cancers7020824 (special issue - Cancer Cell Proliferation) [invited article]

 

107. Ho, C.H., Hsu, J.L., Liu, S.P., Hsu, L.C., Chang, W.L., Chao, C.C.-K., Guh, J.H. Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway. Prostate 75 (13):1454-1466, 2015

 

108. Sun, N.-K.*, Huang, S.-L.*, Lu, H.-P., Chang, T.-C. and Chao, C.C.-K. Integrative transcriptomics-based identification of cryptic drivers of taxol-resistance genes in ovarian carcinoma cells: analysis of the androgen receptor. Oncotarget, 6: 27065-27082, 2015 (*equal contribution)

 

109. Liu, Y.-C., Chang, P.-Y. and Chao, C.C.-K. CITED2 silencing sensitizes cancer cells to cisplatin by inhibiting p53 trans-activation and chromatin relaxation on the ERCC1 DNA repair gene. Nucleic Acids Res. 43: 10760-10781, 2015 (first online: 17 Sep. 2015, doi: 10.1093/nar/gkv934)

 

110. Hung, F.-C.*, Shih, H.-Y.*, Cheng, Y.-C. and Chao, C.C.-K. Growth-arrest-specific 7 gene regulates neural crest formation and craniofacial development in zebrafish. Stem Cells Dev. 24: 2943-2951, 2015 (*equal contribution)

 

111. Lin, Y.-T. and Chao, C.C.-K. Identification of the β-catenin/JNK/prothymosin-alpha axis as a novel target of sorafenib in hepatocellular carcinoma cells. Oncotarget 6: 38999-39017, 2015; DOI: 10.18632/oncotarget.5738

 

112. Chang, PY#, Huang, Y #, Hung, TY, Chong, KY, Chang, YS, Chao, CC-K* and Chow, KPN* Spontaneous metastases in immunocompetent mice harboring a primary tumor driven by oncogene latent membrane protein 1 from Epstein-Barr virus. Biomed J, 39: 261-271, 2016 (#equal contribution, *co-correspondence)

 

113. Chao, C.C.-K.  Inhibition of apoptosis by oncogenic hepatitis B virus X protein: Implications for the treatment of hepatocellular carcinoma. World J. Hepatol. 8(25): 1061-1066, 2016 [invited review]

114. Lin, Y.-T., Liu, Y.-C. and Chao, C.C.-K. Inhibition of JNK and prothymosin-alpha sensitizes hepatocellular carcinoma cells to cisplatin. Biochem. Pharmacol. 122: 80-89, 2016 

1. Chao, C.C.-K. and Rosenstein, B.S. Induction of sister chromatid exchanges in ICR 2A frog cells exposed to monochromatic UV wavelengths (265-313 nm) and photoreactivating light. Environ. Mutagen. (suppl.) 5: 408, 1983. (14th Annual Meeting of Environmental Mutagen Society, San Antonio, Texas, 1983)

 

2. Chao, C.C.-K. and Rosenstein, B.S. Photoreactivation of sister chromatid exchanges in ICR 2A frog cells exposed to 265-313 nm monochromatic UV wavelength. Photochem. Photobiol. 39: 108s, 1984. (9th International Congress on Photobiology / 12th Annual Meeting of American Society for Photobiology, Pheladelphia, Pennsylvania, 1984)

 

3. Chao, C.C.-K. and Rosenstein, B.S. Inhibition of UV-induced sister chromatid exchanges in ICR 2A frog cells by pretreatment with -rays. Radiat. Res., Abstract p.63, 1984. (32nd Annual Meeting of Radiation Research Society, Orlando, Florida, 1984)

 

4. Chao, C.C.-K. and Rosenstein, B.S. Isolation and characterization of a mutant cell line derived from ICR 2A frog cells exposed to the induction of non-dimer DNA damages by solar UV radiation. Photochem. Photobiol. 41: 110s, 1985. (13th Annual Meeting of American Society for Photobiology, New Orleans, Louisiana, 1985)

 

5. Rosenstein, B.S. and Chao, C.C.-K. Use of metabolic inhibitors to investigate the excision repair of pyrimidine dimers and non-dimer DNA damages. Photochem. Photobiol. 41: 108s, 1985. (13th Annual Meeting of American Society for Photobiology, New Orleans, Louisiana, 1985)

 

6. Gething, M.-J., McCammon, K., Normington, K., Chao, C.C.-K. and Sambrook, J. Protein folding and intracellular transport. J. Cell Biol. 103: 291a, 1986. (26th Annual Meeting of American Society for Cell Biology, Washington, D.C., 1986)

 

7. Chao, C.C.-K., Bird, P., Gething, M.-J. and Sambrook, J. Post-translational translocation of influenza virus hemagglutinin. J. Cell Biochem. (suppl) 11A: 253, 1987. (UCLA-Symp. on Molecular Biology of Intracellular Protein Sorting and Organelle Assembly, Toas, New Mexico, 1987)

 

8. Chao, C.C.-K., Gething, M.-J. and Sambrook, J. Mutations at the N-terminus of influenza virus hemagglutinin cause malfolding and prevent transport of the molecule from the endoplasmic reticulum of mammalian cells. J. Cell Biochem. (suppl) 11A: 282, 1987. (UCLA-Symp. on Molecular Biology of Intracellular Protein Sorting and Organelle Assembly, Taos, New Mexico, 1987)

 

9. Gething, M.-J., McCammon, K., Normington, K., Chao, C.C.-K. and Sambrook, J. Protein folding and intracellular transport. J. Cell Biochem. (suppl) 11A: 248, 1987. (UCLA-Symp. on Molecular Biology of Intracellular Protein Sorting and Organelle Assembly, Toas, New Mexico, 1987)

 

10. Chao, C.C.-K. and Lin-Chao, S. Clonogenic assay of photolyase activity in cultured frog cells: Transient induction by 254 nm-UV in arrested cells. Photochem. Photobiol. 45: 74S, 1987. (15th Annual Meeting of American Society for Photobiology, Bal Harbour, Florida, 1987)

 

11. Chao, C.C.-K. and Lin-Chao, S. Regulation of photolyase activity in high population doubling frog cells. Environ. Mol. Mutagen. (suppl) 11: 22, 1988 (19th Annual Meeting of Environmental Metagen Society, Charleston, South Carolina, 1988)

 

12. Chao, C.C.-K. and Lin-Chao., S. Regulation of enzymatic photorepair in eukaryotic cells. (FASEB Summer Research Conference on Cellular and Molecular Genetics, Saxtons River, Vermont, 1988)

 

13. Chao, C.C.-K., Gething, M.-J. and Sambrook, J. Mutations at the N-terminus of influenza virus hemagglutinin cause malfolding and prevent transport of the molecule from the endoplasmic reticulum of mammalian cells. (4th International Congress of Cell Biology, Montreal, Canada, 1988)

 

14. Chao, C.C.-K. and Lin-Chao, S. Transient induction of photolyase activity in cultured frog cells by ultraviolet light. (4th International Congress of Cell Biology, Montreal, Canada, 1988)

 

15. Chao, C.C.-K., Lee, Y.-L., Cheng, P.-W. and Lin-Chao, S. Cisplatin resistance in human cells. J. Cell Biochem. 13 D: 51, 1989. (UCLA-Symp. on Biotechnology and Human Genetic Predisposition to Disease, Steamboat Springs, Colorado, 1989)

 

16. Chao, C.C.-K., Lee, Y.-L., Cheng, P.-W. and Lin-Chao, S. Enhanced DNA repair in HeLa cells resistant to cisplatin. (International Symposium on Drug Resistance Mechanism in Cancer Cells, Taipei, Taiwan, 1989)

 

17. Chao, C.C.-K., Lee, Y.-L., Cheng, P.-W., Yam, W.-C. and Lin-Chao, S. Acquired resistance of human cervical carcinoma cells to cisplatin. (FASEB Summer Research Conference on Molecular Mechanisms of Carcinogenesis, Copper Mountain, Colorado, 1989)

 

18. Chao, C.C.-K. Drug resistance in human cells: Cisplatin and multidrug resistance.  (International Congress on Molecular Biology of Human Genetic Diseases, Taipei, Taiwan, 1989)

 

19. Chao, C.C.-K. and Lin-Chao, S. Development of cisplatin resistance in HeLa cells accompanies enhanced expression of transfected CAT gene carrying cisplatin damage. J. Cell Biochem. (suppl) 14A: 349, 1990. (UCLA-Symp. On Manipulating the Mammalian Genome, Tamarron, Colorado, 1990)

 

20. Chao, C.C.-K., Cheng, P.-W., Li, L.-Y., Yam, W.-C. and Lin-Chao, S. Enhanced DNA repair is a mechanism for acquired cisplatin resistance in human cervical carcinoma cells. (SCBA Third International Symposium & Workshop, Hong Kong, 1990)

 

21. Chao, C.C.-K., Cheng, P.-W., Lee, L.-Y., Huang, S.-L. and Lin-Chao, S. The overexpression of cisplatin-modified DNA binding factors in cisplatin resistant HeLa cells. (The First Asian Conference on Transcription, Taipei, Taiwan, 1990)

 

22. Chao, C.C.-K., Lee, L.-Y., Cheng, P.-W., Huang, S.-L., Shyur, L.-F. and Lin-Chao, S. The overexpression of cisplatin-modified DNA binding factors in cisplatin resistant HeLa cells. Abstract p.137 (Sixth International Symposium on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy, San Diego, 1991)

 

23. Chao, C.C.-K., Huang, S.-L., Shyur, L.-F., Lee, L.-Y., Cheng, P.-W., M.H.L. Young and Lin-Chao, S. Induction and overexpression of damaged-DNA binding proteins in cisplatin resistant HeLa cells. J. Cell Biochem. 15D: 100, 1991. (Keystone Symposia on Genomic Instability and Cancer, Tamarron, Colorado, 1991)

 

24. Huang, S.-L. and Chao, C.C.-K Ca2+-mediated inhibition of a nuclear protein that recognizes UV-damaged DNA and is constitutively overexpressed in resistant human cells: DNA-binding assay. Abstract #382 (p.106) (The Seventh Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, 1992)

 

25. Sun, N.-K. and Chao, C.C.-K. Characterization of a DNA damage recognition protein from F9 teratocarcinoma cells, which is inducible by retinoic acid and cAMP. Abstract #387 (p.107) (The Eighth Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, 1993)

 

26. Chao, C.C.-K., Yam, W.-C. and Sun, N.-K. A direct-repeat sequence is required for up-regulation of the human BiP gene by brefeldin A, tunicamycin and calcium ionophore A23187. J. Cell Biochem. 17A: 104, 1993. (Keystone Symposia on Transcription: Factors, Regulation and Differentiation, Keystone, Colorado, 1993)

 

27. Chao, C.C.-K., Sun, N.-K. and Huang, S.-L. DNA-damage recognition protein as a potential marker of genotoxic resistance. Abstract #S14 (p.29) (The Joint Conference of AACR/IBMS on Modern Developments in Cancer Therapeutics,Taipei, Taiwan, 1994 Nov. 7-11)

 

28. Ju, Y.-T., Chang, A.C.Y., Tsaur, M.-L., Chao, C.C.-K., Hwang, H.-M., Cohen, S.N. and Lin-Chao, S. gas7: a mouse gene expressed preferentially during growth arrest of fibroblasts and in terminally differentiated neurons affects neurite formation during neuron development. Gurdon Research Conference on Human Molecular Genetics, 1997 August 15-20

 

29. Chao, C.C.-K. Molecular basis of cisplatin resistance: cell model studies.     Asstract #S9 (p.24) (Invited lecture, The Seventh Symposium on Recent     Advances in Cellular and Molecular Biology, Kenting, Taiwan, 1999 Jan. 30-Feb. 1)

 

30. Kamarajan, P., Sun, N.-K. and Chao, C.C.-K. Activation of MAP kinases and PKA by cisplatin: modulation of resistance by PKA modultors and relation to apoptyosis in cervix carcinoma HeLa cells. Asstract #P80 (p.72) (The Seventh Symposium on Recent Advances in Cellular and Molecular Biology, Kenting, Taiwan, 1999 Jan. 30-Feb. 1)

 

31. Chao, C.C.-K., Kuo, J.-T., Su, L.-J., Su, B.W., Liu, C.-H., Lih, C.-J. and Lin-Chao, S. Transient expression of GAS7 is induced by NGF and is required for NGF-mediated neurite outgrowth in PC12 cells. Asstract #P133 (p.107) (The Eighth Symposium on Recent Advances in Cellular and Molecular Biology, Kenting, Taiwan, 2000 Jan. 29-31)

 

32. Su, L.-J., Lin-Chao, S. and Chao, C.C.-K. Transient induction of GAS7 is required for neurite outgrowth by NGF that occurs asynchronously in PC12 cells. Asstract #P72 (p.76) (The Eighth Symposium on Recent Advances in Cellular and Molecular Biology, Kenting, Taiwan, 2000 Jan. 29-31)

 

33. Lee, S.-S., Ueng, S.W.-N., Shih, C.-H. and Chao, C.C.-K. Signal transduction pathway and apotosis in bacteria-infected chondrocytes. (The 46th Annual Meeting of Orthopaedic Research Society, Orlando, Florida, 2000 March 12-15)

 

34. Sun, N.-K. and Chao, C.C.-K. PKC-dependent phosphorylation of HMG-1 reduces damaged-DNA recognition that is associated with cisplatin resistance in mammalian cells. Abstract #P278 (p.233) (The 15th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, 2000 March 25-26)

 

35. Sun, N.-K., Lu, H.-P. and Chao, C.C.-K. Overexpression of DDB2 enhances DNA-damage recognition and confers UV resistance in mammalian cells. Abstract #P321 (p.244) (The 15th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, 2000 March 25-26)

 

36. Lee, M.S., Yen, C.Y., Yuan, L.J., Chan, Y.S., Ueng, S.W.N., Shih, C.H., Chao, C.C.-K. and Smith, R.L. Induction of apoptosis by mechanical stress in human osteoarthritic chondrocytes. (Joint Meeting, Orthopaedic Association, Joint Reconstruction Society, Orthopaedic Research Society, and Chinese Speaking Orthopaedic Society, R.O.C., Taipei, Taiwan, 2000 October 14)

 

37. Kamarajan, P., Sun, N.-K., Sun, C.-L. and Chao, C.C.-K. Damaged DNA binding protein 2 (DDB2), a partner of HBx-associated protein 1 (XAP-1), inhibits TNF receptor-mediated death signals. Abstract P31 (p.31) (The Joint Conference of NHRI/AACR on Hepatitis and Hepatocellular Carcinoma: Novel Approaches, Taipei, Taiwan, 2000 Dec. 8-10)

 

38. Kamarajan, P., Sun, N.-K., Sun, C.-L. and Chao, C.C.-K. Damaged-DNA binding protein 2 (DDB2), a DNA repair protein, inhibits UV and TNF receptor-mediated death signals. (The 4th Asia-Pacific International Molecular Biology Network (A-IMBN), Taipei, Taiwan, 2001 Nov. 3-4)

 

39. Sun, C.-L., Kamarajan, P., Sun, N.-K. and Chao, C.C.-K. DDB2, a DNA repair protein, is proteolytically processed, and inhibits UV and receptor-mediated death signals. (The Tenth Symposium on Recent Advances in Cellular and Molecular Biology, Kenting, Taiwan, 2002 Jan. 25-28)

 

40. Sun, C.-L., Kamarajan, P., Sun, N.-K. and Chao, C.C.-K. DDB2, a DNA repair protein, is proteolytically processed, and inhibits UV and TNF receptor-mediated death signals. (The 4th Asia-Pacific Organization for Cell Biology Congress (APOCB), Taipei, Taiwan, 2002 Nov. 3-6)

 

41. Sun, C.-L., Kamarajan, P., Sun, N.-K. and Chao, C.C.-K. Nuclear localization of DDB2, through potentiating cFLIP expression in UV-treated cells, is required for anti-apoptosis. Abstract #P262 (The 19th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, 2004 April 10-11)

 

42. Sun, C.-L. and Chao, C.C.-K. Cross-resistance to death ligand-induced apoptosis in cisplatin-selected HeLa cells associated with overexpression of DDB2 and subsequent induction of cFLIP. (The 13th Symposium on Recent Advances in Cellular and Molecular Biology, Kenting, Taiwan, 2005 Jan. 26-28)

 

43. Huang, B.-T.*, Chang, P.-Y.*, Woo, W.-M., Lin-Chao, S.** and Chao, C.C.-K.** Gas7 mutation impairs motor behavior of mutant mice during aging. (*equal contribution, **correspondence) (The Cold Spring Harbor Laboratory Meeting – Axon guidance, synaptogenesis and neural plasticity, New York, USA, 2006 Sep. 13-17)

 

44. Wu, Z.-Z., Lu, H.-P. and Chao, C.C.-K. Identification and functional analysis of cisplatin resistance genes by shRNA silencing of genes upregulated in cisplatin-selected HeLa cells. Abstract #P761 (The 24th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, 2009 March 22)

 

45. Wu, Z.-Z. and Chao, C.C.-K. Synthetic lethality by lentiviral short hairpin RNA silencing of ER localized NAPA/SNAP-α and cisplatin in chemoresistant cells. Abstract #P762 (The 24th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, 2009 March 22)

 

46. Kuo, T.-C. and Chao, C.C.-K. Sensitization to anticancer drugs by shRNA silencing of oncogenic HURP: potential involvement of p53 in response to mitotic damage. Abstract #P780 (The 24th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, 2009 March 22)

 

47. Huang, B.-T., Su, W.B., Chang, P.-Y., Su, C.-H., Chao, C.C.-K. and Lin-Chao, S. Gas7 is involved in

regulation of endplate structure and muscle fiber type determination. Mech. Develop. 126: S137-S138, 2009 (DOI: 10.1016/j.mod.2009.06.287) Abstract 07-P004 (16th International Society of Developmental Biologists Congress, Edinburgh, Scotland, U.K., 2009 Sep. 6-10)

 

48. Kuo, T.-C., Lee, C.-J., Lin, Y.-T., Chang, P.-Y. and Chao, C.C.-K. Improving hepatocellular carcinoma chemotherapy by silencing hepatitis B virus X target genes. Abstract #P??? (The 26th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, 2011 March 19)

 

49. Lin, Y.-T. and Chao, C.C.-K. The functional roles of prothymosin alpha in chemoresistance of hepatocellular carcinoma. Abstract#P345 (The 28th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, 2013 March 23)

 

50. Liu, Y.-C. and Chao, C.C.-K. Knockdown of CITED2 using short-hairpin RNA impairs DNA repair and sensitizes cisplatin chemotherapy thought down- regulation of DNA repair genes. Abstract#P844 (The 28th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, 2013 March 23)

 

51. Lin, Y.-T. and Chao, C.C.-K. Silencing of prothymosin alpha sensitizes hepatocellular carcinoma cells to sorafenib by attenuating ERK andβ-catenin signals and by activating the Bax/caspase-9 pathway. (The 7th Asian Pacific Organization of Cell Biology (APOCB) Workshops, National University of Singapore (NUS), Singapore, 2014 Feb 24-27)

 

52. Chang, P.-Y.*, Hung, F.-C.*, Tu, S.-J., Lin-Chao, S. and Chao, C.C.-K. Disruption of gas7 gene expression impairs osteogenic differentiation of mouse mesenchymal stem cells and osteoblasts associated with reduction in the tibia trabecular bone of older mice. Abstract#P??? (The 29th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, 2014 March 15-16) (*equal contribution)

 

53. Lin, Y.-T. and Chao, C.C.-K. Oncogenic c-myc/max and b-catenin/TCF4/AP-1 complex against sorafenib-induced cell death through up-regulation of prothymosin-alpha in HCC cells. Poster#?? (Cold Spring Harbor Asia Conferences: Precision Cancer Biology and Medicine, Suzhou, China May 4-8, 2015)

B. 研討會論文 (Meeting papers)

C. 專書及綜論(Book chapters & review)

1. Chao, C.C.-K. Chromosomal Banding in Cultured Hamster V-79 Cells. M.S. Thesis, National Tsing Hua University清華大學, Taiwan, 1981

 

2. Chao, C.C.-K. Repair of Non-dimer DNA Damages in ICR 2A Frog Cells Exposed to Solar Ultraviolet Radiation in the Mid-UV (290-320 nm) Range. Ph.D. Dissertation, University of Texas Southwestern Medical Center, U.S.A., 1985

 

3. Chao, C.C.-K. and Lin-Chao, S. Biology of Solar-UV Radiation. 日光紫色輻射生物學Taipei: Hwa Shiang Yuan華香園出版社, 1988 (The Chinese edition based on J. Jagger's Solar-UV Actions on Living Cells, Praeger, 1985; Ed. National Institute of Compilation and Translation國立編譯館, Republic of China).

 

4. Chao, C.C.-K., Bird, P., Gething, M.-J. and Sambrook, J. Uncoupling of translocation across microsomal membranes from biosynthesis of influenza virus hemagglutinin. In: Molecular Biology of Intracellular Protein Sorting and Organelle Assembly, (UCLA Symp. Molec. Cell. Biol.) pp. 85-91, New York: Alan R. Liss, Inc., 1988.

 

5. Chao, C.C.-K. Increase in damaged-DNA binding and repair in human UV resistance. In: Trends in Photochemistry and Photobiology 1: 341-351, ed. Council of Scientific Research Integration, India, India: Research Trends, 1991.

 

6. Chao, C.C.-K. Overproduction of damage-recognition proteins in human cells resistant to cisplatin and ultraviolet. In: Gene Amplification in Mammalian Cells: A Comprehensive Guide, pp. 131-139, ed. R.E. Kellems, USA: Marcel Dekker, Inc., 1993.

 
7. Chao, C.C.-K. Molecular basis of cis-diamminedichloroplatinum(II) resistance: a review. J. Formosan Med. Assoc. 95: 893-900, 1996.

8. Sun, N.-K. and Chao, C.C.-K. The cytokine activity of HMGB1, extracellular escape of the nuclear protein (a review). Chang Gung Med. J. 28: 673-682, 2005

 

9. Chao, C.C.-K. Gas7. AfCS-Nature Molecular Page, 2006 (A000068, doi:00.0000/ mp.g000000.00)

 

10. Chao, C.C.-K. Hmg1. AfCS-Nature Molecular Page, 2006 (A001133, doi:00.0000/mp.h000000.00)

11. Chao, C.C.-K. A Search for the genes involved in resistance to cisplatin chemotherapy: Review of the experimental evidence. Curr. Top. Pharmacol. 14: 47-54, 2011 January [invited review article]

 

12. Chao, C.C.-K. The role of DDB2 in regulating cell survival and apoptosis following DNA damage - a mini-review. In DNA Repair (ed., Kruman, I.), InTech: 2011 July (ISBN 978-953-307-697-3) [invited review book chapter]

 

13. Chao, C.C.-K. Chondrogenic differentiation of human mesenchymal stem cells: Role of human growth-arrest-specific protein, SOX9, and extracellular signal-regulated kinase. In Stem Cells and Cancer Stem Cells: Therapeutic Applications in Disease and Injury (ed., Hayat, E.), Springer: 2011 [invited book chapter] dis-connected??

14. Chao, C.C.-K. Adapting new ways to escape attacks by anti-cancer drugs: Epigenetic changes and alternative splicing. Adaptive Medicine 4: 64-68, 2012 [invited review]

 

15. Lu, H.-P. and Chao, C.C.-K. Cancer cells acquire resistance to anticancer drugs: An update. Biomed. J. 35: 479-491, 2012 [invited review]

 

16. Chao, C.C.-K, Hung, F.C. and Chao, J.J. Gas7 is required for mesenchymal stem cell-derived bone development. Stem Cells Int. 2013, Article ID 137010. doi:10.1155/2013/137010 [invited review] [originally for cancelled special issue: “New insights into bone development and repair and mesenchymal stem cell differentiation” (eds., Gaël Y. Rochefort, Laoise Mcnamara, Bruno Péault)]

17. Huang, S.-L. and Chao, C.C.-K. Linking immunophilin FKBP5 to taxol resistance in ovarian cancer. Cancer Cell & Microenviron. 2015; 2: e692. doi: 10.14800/ccm.692 [invited research highlight]

 

18. Chao, C.C.-K. Mechanisms of p53 degradation. Clinica Chimica Acta 438: 139-147, 2015 (first online: 13 Aug. 2014, doi: 10.1016/j.cca.2014.08.015) [invited review]

 

19. Lin, Y.-T. and Chao, C.C.-K. Sorafenib induces apoptosis in hepatocellular carcinoma Cells by inhibiting c-Myc and prothymosin-alpha. Cancer Cell & Microenviron. 2015; 2: e788. doi: 10.14800/ccm.788 [invited research highlight]

20. Chao, C.C.-K. Prevention of apoptosis by oncogenic HBx: laboratory observations reveal implications in HCC chemoresistance. World J. Hepatol. 8(25): 1061-1066, 2016 [invited review]

D. 基因、蛋白序列及体學分析資料 (Sequences & omics submission)

    Nucleotide sequence submissions to GenBank
 
  1. Chao, C.C.-K., Homo sapiens BiP/GRP78 promoter (670 nt). The EMBL Data Library accession number X59969, 1991
  2. Chao, C.C.-K., Homo sapiens mRNA for BiP protein (2554 nt). The EMBL Data Library accession number X87949, 1995
  3. Chao, C.C.-K., Homo sapiens mRNA for xeroderma pigmentosum complementing group E protein (3723 nt). The EMBL Data Library accession number AJ002955, 1997
  4. Chao, C.C.-K., Rattus norvegicus mRNA for GAS-7 protein (2618 nt). The EMBL Data Library accession number AJ002955, 1997
  5. Chao, C.C.-K., Saccharomyces serevisiae mRNA for cisplatin-damaged DNA recognition protein CDRP1 (1087 nt). The EMBL Data Library accession number AJ223169, 1998
  6. Chao, C.C.-K., Homo sapiens mRNA for GAS-7 protein (2427 nt). The EMBL          Data Library accession number AJ224876, 1998
  7. Chao, C.C.-K., Rattus norvegicus mRNA for GAS-7 protein, full length (6412 nt). The EMBL Data Library accession number AJ131902, 1998
  8. Chao, C.C.-K. Rattus norvegicus mRNA for damage-specific DNA binding protein 1 (DDB1 gene) (3850 nt). The EMBL Data Library accession number AJ277077, 2000
  9. Chao, C.C.-K. Mus musculus mRNA for damaged-DNA recognition protein 1 (Ddb1 gene) (4179 nt). The EMBL Data Library accession number AJ416426, 2001
  10. Chao, C.C.-K., Homo sapiens mRNA for caspase-9c protein (1111 nt). The EMBL Data Library accession number AJ781267, 2004
  11. Chao, C.C.-K. and Sun, N.-K. Zebrafish (Danio rerio) mRNA for Gas7 (1631 nt). The GenBank Accession Number JQ713002, 2012

 

   cDNA microarray platform submissions to GEO (Gene Expression Omnibus)

 
  1. LuHP, Chao CC. Gene expression in cisplatin resistance HeLa cells. The NCBI GEO Accession Number GSE15120, 2009 Mar 5 [Plateform GPL1392, 6 Samples; release to public 2010 Mar 5]
  2. Huang SL, Sun NK, Lu HP, Chao CC. Gene expression in taxol resistance SKOV3 cells (I). The NCBI GEO Accession Number GSE58840, 2014 July 27 (included in GSE58878) [release to public 2016 Dec 31]
  3. Huang SL, Sun NK, Lu HP, Chao CC. Gene expression in taxol resistance SKOV3 cells (II). The NCBI GEO Accession Number GSE58877, 2014 July 27 (included in GSE58878) [release to public 2016 Dec 31]
  4. Huang SL, Sun NK, Lu HP, Chao CC. Gene expression in taxol resistance SKOV3 cells (primary). The NCBI GEO Accession Number GSE60335, 2014 Aug. 12 (release to public 2016 Dec 31)
     
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