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細胞生物學 Cell Biology (BMM425)

課程負責人: 趙清貴 (分機: 5157)

學分: 3小時

時間: 星期一上午 9:10 - 12:00

地點: M0203

 

  「細胞生物學」(Cell Biology)的內容涵蓋三大部分。第一部分是細胞生物學探討所運用的技術。第二部分是關於細胞生物學的核心,主要介紹真核細胞的共同特性,也就是細胞的內部結構。第三部分是關於多細胞生物的細胞行為:包括細胞之間的連結(junctions)、細胞外間質(extracellular matrix),細胞分化、發育,以及多細胞結構的病變,如癌症等。

 

Date                           Topics                                                                                         Instructor   Chapters

 

Part I: Introduction to the cell and methods

 

2016-09-12               Cells, genomes, cell chemistry and bioenergetics                            趙清貴   1, 2

 

2016-09-19               Analyzing cells/molecules/systems and visualizing cells*               趙清貴   8, 9

 

Part II: Internal organization of the cell

 

2016-09-26               Membrane structure, transport and electrical propertiesy*               陳景宗   10, 11

 

2016-10-03                Intracellular compartments and protein sorting                               洪錦堂   12

 

2016-10-17                Intracellular membrane traffic                                                          洪錦堂   13

2016-10-24                Energy conversion: mitochondria                                                     周美智   14

 

2016-10-31                 Cell signaling                                                                                   余兆松   15

 

2016-11-07                 The cytoskeleton                                                                              歐陽品   16

 

2016-11-14                 The Cell cycle                                                                                  趙清貴   17  

 

2016-11-21                 Cell death                                                                                         趙清貴   18

2016-11-28                 Cell junction, adhesion and the extracellular matrix                       歐陽品   19

 

Part III: Cells in their social context

 

2016-12-05                  Cancer                                                                                            趙清貴    20

 

2016-12-12                  Development of multicellular organisms                                       白麗美    21

 

2016-12-19                  Stem cells and tissue renewal                                                         趙清貴    22

 

2016-12-26                  Infection and innate immunity                                                        郭敏玲    24

 

2017-01-09                  The adaptive immunity                                                                   郭敏玲    25

 

PS:

10/10 國慶假; 2017/01/02 年假; 1/22 成績繳交; *互調 9/19 陳景宗

 

教科書: Alberts, B. et al. (2014) Molecular Biology of the Cell, 6th ed., Garland, New York。参考書: Lodish, H. et al. (2013) Molecular Cell biology (7th ed., Freeman, New York)。另外可由任課老師補充新的重要文獻。

成績考核: 按各章小考(take-home)成績平均。

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